Healthcare Careers in Sioux FallsSouth Dakota

Sioux Falls is the largest city in South Dakota and a major healthcare hub, home to both Sanford Health and Avera Health headquarters. The city offers urban amenities with a small-town feel and one of the lowest unemployment rates in the nation.

Population203,469
Cost of LivingBelow Avg
Overall GradeA

Sioux Falls at a Glance

🏆
A
Overall
💵
A
Cost of Living
🏥
A
Healthcare
🏠
A-
Housing
💼
A+
Job Market

Cost of Living

88
IndexVery Affordable

Sioux Falls's cost of living is 12% below the national average.

🏠 Median Rent$1,050
🏡 Median Home Price$285,000
🛒 Groceries90
💡 Utilities85
🚗 Transportation92

Index: 100 = National Average. Lower values indicate more affordable costs.

Salary & Purchasing Power

125Purchasing Power

Your salary goes 25% further in Sioux Falls compared to the national average.

👩‍⚕️Registered Nurse
Base Salary$68K
Adjusted Value
$77K+$9K
👨‍⚕️Physician
Base Salary$270K
Adjusted Value
$307K+$37K
🔬Medical Technician
Base Salary$48K
Adjusted Value
$55K+$7K

Adjusted salary represents equivalent purchasing power based on local cost of living.

Top Healthcare Employers in Sioux Falls

S

Sanford Health

Hospital

4.3(892 reviews)
Featured

Sanford Health is one of the largest health systems in the United States, headquartered in Sioux Falls. With 47 hospitals and nearly 50,000 employees across SD, ND, MN, and other states, Sanford offers unparalleled career growth opportunities.

👥 1000+ employees💼 450 open positions
Sign-on BonusTuition ReimbursementLoan Repayment+2 more
A

Avera Health

Hospital

4.4(756 reviews)
Featured

Avera Health is a regional health ministry headquartered in Sioux Falls, operating hospitals and clinics across South Dakota, Iowa, Minnesota, Nebraska, and North Dakota. Known for excellent employee satisfaction and community focus.

👥 1000+ employees💼 380 open positions
Mission-Driven CultureTuition AssistanceWellness Programs+2 more

What Healthcare Workers Say

M

Michelle T.

Registered Nurse

6 years in the area

Sioux Falls has everything - great hospitals, affordable housing, and a wonderful community. Sanford Health has been an amazing place to build my career.

D

Dr. Robert K.

Hospitalist

4 years in the area

Moving here from Minneapolis was the best decision. Similar opportunities but much lower cost of living. My family loves the schools and safe neighborhoods.

Living and Working in Sioux Falls

Sioux Falls, South Dakota offers healthcare professionals a unique opportunity to build a rewarding career while enjoying the benefits of an affordable cost of living. With 2 major healthcare employers, there are ample opportunities for professional growth.

Whether you are a registered nurse, physician, medical technician, or allied health professional, Sioux Falls provides a supportive environment for your healthcare career with competitive compensation and a strong sense of community.

🚀

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Data Sources & Methodology

The data presented on this page is compiled from multiple authoritative sources to provide accurate and up-to-date information about healthcare careers and cost of living. Grade ratings are calculated based on a weighted algorithm combining multiple quality-of-life factors.

Salary data represents averages and may vary based on experience, employer, and specific position. Cost of living indices are relative to the national average (100).

Frequently Asked Questions

What healthcare jobs are available in Sioux Falls, South Dakota?
Sioux Falls offers healthcare positions including registered nurses, physicians, medical technicians, home health aides, and various allied health roles across hospitals, clinics, and healthcare facilities.
What is the cost of living in Sioux Falls compared to other cities?
Sioux Falls has a cost of living index of 88, which is 12% below the national average.
What is the average nurse salary in Sioux Falls?
The average registered nurse salary in Sioux Falls, South Dakota is approximately $68,000 per year, though this can vary based on experience, specialty, and employer.
How big is Sioux Falls, South Dakota?
Sioux Falls has a population of approximately 203,469 residents, offering a larger city atmosphere with healthcare opportunities.