RN Job Pulse

Sioux Falls RN Job Pulse

Live registered nurse openings, employer demand, and salary context for Sioux Falls, SD.

Live openings
74
Hiring employers
2
Average salary
$86,070

Demand Snapshot

Low $64,553
Median $87,791
High $116,195
+0% vs national

Current RN jobs in Sioux Falls

These are live healthcare jobs tied to Sioux Falls, SD and filtered toward registered nurse demand.

Locum Tenens Jobs

Registered Nurse (RN) or Licensed Practical Nurse (LPN) | UroGyn Clinic

Avera HealthPosted Jul 7
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Night shift$6,000 sign-on

Location: Avera Urogynecology Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $22.50 - $41.25 Position Highlights Monday-Friday,...

Pay

$22.5-41.25/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Registered Nurse (RN) or Licensed Practical Nurse (LPN) | OBGYN Clinic Float

Avera HealthPosted Jul 7
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Flexible

Location: Avera Obstetrics & Gynecology Plaza 1 Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $22.50 - $41.25 Position Highlights You Belong at Avera...

Pay

$22.5-41.25/hr

Location

Sioux Falls, SD

View details
Locum Tenens Jobs

Registered Nurse (RN) | OR/Surgery | Avera Specialty Hospital

Avera HealthPosted May 13
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Evening shift

Location: Avera Specialty Hospital-Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $31.00 - $46.25 Position Highlights OR/Surgery:...

Pay

$31-46.25/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Registered Nurse (RN) | Pre/Post Recovery Avera Specialty Hospital | PRN

Avera HealthPosted Jul 9
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Evening shift

Location: Avera Specialty Hospital-Sioux Falls Worker Type: PRN Work Shift: Primarily days with possible weekends/evenings/holidays (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $31.00 -...

Pay

$31-46.25/hr

Location

Sioux Falls, SD

View details
Locum Tenens Jobs

Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | Neurology Clinic

Avera HealthPosted Jul 9
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Day shift$6,000 sign-on

Location: Avera Medical Group Neurology-Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $20.00 - $41.25 Position Highlights RN and LPN may...

Pay

$20-41.25/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Home Infusion Registered Nurse (RN)|MCK Home Infusion (PRN)

Avera HealthPosted May 17
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Flexible

Location: Avera Home Infusion Pharmacy-Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $27.75 - $41.25 Position Highlights Varied Shifts,...

Pay

$27.75-41.25/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Registered Nurse (RN - III)|MCK Emergency Unit

Avera HealthPosted Jul 9
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Night shift$6,000 sign-onWeekends required

Location: Avera McKennan Hospital Worker Type: Regular Work Shift: Rotating days/evenings/nights/weekends/holidays (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $32.50 - $48.50 Position...

Pay

$32.5-48.5/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Registered Nurse (RN) | Short Stay Unit

Avera HealthPosted Jul 10
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Night shift$15,000 sign-on

Location: Avera McKennan Hospital Worker Type: Regular Work Shift: Night Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $32.50 - $48.50 Position Highlights Straight NIGHT position. 12...

Pay

$32.5-48.5/hr

Location

Sioux Falls, SD

View details
Locum Tenens Jobs

Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Plastic Surgery Clinic

Avera HealthPosted Jul 8
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Flexible$6,000 sign-on

Location: Avera Plastic & Reconstructive Surgery Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $22.50 - $41.25 Position Highlights May be eligible...

Pay

$22.5-41.25/hr

Location

Sioux Falls, SD

View details
Locum Tenens Jobs

Registered Nurse (RN) | Behavioral Health Child Unit

Avera HealthPosted Jul 11
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 13Night shift$15,000 sign-onWeekends required

Location: Avera Behavioral Health Sioux Falls Worker Type: Regular Work Shift: Evening and Night Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $32.50 - $48.50 Position Highlights...

Pay

$32.5-48.5/hr

Location

Sioux Falls, SD

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RN - Registered Nurse - Hospital Outpatient Scheduling - Patient Appointment Center - Part Time

Sanford HealthPosted Jul 12
Full-timeMid Level
Compact license eligibleVerified Jul 13Day shift

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland. Work Shift: Day (United States of America) Scheduled Weekly Hours: 24...

Pay

$32-48/hr

Location

Sioux Falls, SD

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Locum Tenens Jobs

Registered Nurse (RN) - Quality Specialist

Avera HealthPosted May 17
Full-timeEntry LevelMid Level
Compact license eligibleVerified Jul 10Flexible

Location: Avera McKennan Hospital Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience. $64,480.00 - $96,200.00 Position Highlights You Belong at Avera Be...

Pay

$64,480-96,200/yr

Location

Sioux Falls, SD

View details

Employer Pulse

Who is hiring registered nurses

Employer count is computed from live aggregated openings in Sioux Falls, SD, not a static employer list.

Avera HealthSanford Health

Data Sources & Methodology

The data presented on this page is compiled from multiple authoritative sources to provide accurate and up-to-date information about healthcare careers and cost of living.

Last updated: 2026-03-25T14:25:32.532Z

Salary data represents averages and may vary based on experience, employer, and specific position. Cost of living indices are relative to the national average of 100.